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刊物信息

期刊名称:药物分析杂志
主管单位:中国科学技术协会
主办单位:中国药学会
承办:中国食品药品检定研究院
主编:金少鸿
地址:北京天坛西里2号
邮政编码:100050
电话:010-67012819,67058427
电子邮箱:ywfx@nicpbp.org.cn
国际标准刊号:ISSN 0254-1793
国内统一刊号:CN 11-2224/R
邮发代号:2-237
 

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中药快速分析技术的发展及其前景

Development and prospect of the rapid analysis technology for traditional Chinese medicine

作者(英文):
分类号:R917
出版年·卷·期(页码):2018,38 (9):1476-1483
DOI: 10.16155/j.0254-1793.2017.01.01
-----摘要:-------------------------------------------------------------------------------------------

为中药快速分析技术的发展与应用提供科学参考依据。查阅近10年与中药快速分析相关的文献,作者总结归纳发现,近10年以近红外光谱分析技术为代表的中药快速分析技术发展迅速,电子鼻、电子舌等技术丰富了中药的快速分析,中药快速分析技术趋于系统化、标准化、智能化,并向中药生产、加工、成品检测中的应用方向发展。中药快速分析技术及其相关的软件、硬件以及基础理论有待完善和开拓,中药快速分析技术仍持续发展,其发展前景良好。

-----英文摘要:---------------------------------------------------------------------------------------

To provide a scientific basis for the development and application of the rapid analysis technology for traditional Chinese medicine. Literatures related to the rapid analysis of traditional Chinese medicine recent was retrieved and a summary was made. The rapid analysis technology for traditional Chinese medicine, in resent ten years, represented by near-infrared spectroscopy analysis technology, has been developing rapidly and enriched by electronic nose, electronic tongue and other technologies, which tends to be systematic, standardized, intelligent and develops towards the applications in Chinese medicine production, processing and finished product testing. Rapid analysis of traditional Chinese medicine technology and the related software, hardware and basic theory need to be further improved and developed. Rapid analysis of traditional Chinese medicine technology is still developing rapidly and the development prospect is optimistic.

-----参考文献:---------------------------------------------------------------------------------------
[1] 段金芳,肖洋,刘影,等.一测多评法与电子眼和电子舌技术相结合优化山茱萸蒸制时间[J].中草药,2017,48(6):1108 DUAN JF,XIAO Y,LIU Y,et al.Optimization of steaming time of Cornus officinalis by QAMS combined with electronic-eye and electronic-tongue techniques[J].Chin Tradit Herb Drug,2017,48(6):1108
[2] 张露.光纤传感过程分析在药物再评价及固有溶出和肠吸收相关性研究[D].乌鲁木齐:新疆医科大学,2016 ZHANG L.The Study of Optical Fiber Sensing Process Analysis in Drug Revaluation and Correlation of Intrinsic Dissolution and Intestinal Absorption[D].Ulumqi:Xinjiang Medical University,2016
[3] 王庆振.毛细管微萃取-光纤传感-微顺序注射在线分析异丙酚[D].乌鲁木齐:新疆医科大学,2016 WANG QZ.On-line Analysis of Propofol by Capillary Microextraction-fiber Sensing-micro-sequential Injection[D]. Ulumuqi:Xinjiang Medical University,2016
[4] 靳露.光纤传感技术结合紫外光谱相似度在药物快检中的应用研究[D].乌鲁木齐:新疆医科大学,2011 JIN L.Study on the Application of Optic-fiber Sensing Technology and the UV Similarity in Drug Rapid Test[D].Ulumqi:Xinjiang Medical University,2011
[5] HAN BX,PENG HS,YAN H.Identification of medicinal Mugua origin by near-infrared spectroscopy combined with partial least-squares discriminant analysis[J].Pharmacogn Mag,2016,12(46):93
[6] 张敏,韩正洲,严萍,等.基于近红外漫反射光谱的鸡血藤药材定性分析[J].世界科学技术-中医药现代化,2014,16(7):1941 ZHANG M,HAN ZZ,YAN P,et al.Qualitative identification of Spatholobus suberectus by near-infrared spectroscopy[J].World Sci Technol Mod Tradit Chin Med Mater Med,2016,16(7):1941
[7] 蒙杰丹,杨季冬.近红外漫反射光谱法对益母草颗粒的定量和定性分析[J].光谱实验室,2012,29(2):1182 MENG JD,YANG JD.Quantitative and qualitative analysis of motherwort granules by near-infrared diffuse reflectance spectroscopy[J].Chin J Spectrosc Lab,2012,29(2):1182
[8] 韩莹,毕福钧,侯惠婵,等.近红外光谱法鉴别何首乌真伪的应用研究[J].中国中药杂志,2014,39(22):4394 HAN Y,BI FJ,HOU HC,et al.Application of near-infrared spectroscopy to identify authenticity of Polygonum multiflorum[J].China J Chin Mater Med,2014,39(22):4394
[9] 付小环,胡军华,李家春,等.应用近红外光谱技术对茯苓药材进行定性定量检测研究[J].中国中药杂志,2015,40(2):280 FU XH,HU JH,LI JC,et al.Qualitative and quantitative detection of Poria cocos by near-infrared reflectance spectroscopy[J].China J Chin Mater Med,2015,40(2):280
[10] 杨海龙,臧恒昌,胡甜,等.近红外漫反射光谱法对不同产地山楂的定性鉴别和定量分析[J].药物分析杂志,2014,34(3):396 YANG HL,ZANG HC,HU T,et al.Classication and quantication analysis of hawthorn from different origins with near-infrared diffuse reflection spectroscopy[J].Chin J Pharm Anal,2014,34(3):396
[11] 蔡佳良,黄洁燕,邓婉婷,等.近红外光谱法快速测定广藿香中醇溶性浸出物含量[J].中国药学杂志,2012,47(24):2026 CAI JL,HUANG JY,DENG WT,et al.Rapid determination of ethanol extracts content of Pogostemon cablin(Blanco) Benth.by near-infrared spectroscopy[J].China J Chin Mater Med,2012,47(24):2026
[12] 贾灿潮,卢慧娟,刘喜乐,等.NIRS法快速测定制何首乌中醇溶性浸出物的含量[J].药物分析杂志,2016,36(3):554 JIA CC,LU HJ,LIU XL,et al.Rapid determination of ethanol extract content in Polygoni Multiflori Radix Praeparata by NIRS[J].Chin J Pharm Anal,2016,36(3):554
[13] 李蕾蕾,林萍,王海霞,等.近红外光谱法快速测定枇杷叶浸出物的含量[J].医药导报,2014,33(2):231 LI LL,LIN P,WANG HX,et al.Rapid determination of ethanol extracts content in Eriobotrya japonica by near-infrared spectroscopy[J].Her Med,2014,33(2):231
[14] 雷敬卫,张强,白雁,等.筋骨痛消丸中醇浸出物的近红外光谱法快速测定[J].北京中医药大学学报,2014,37(11):786 LEI JW,ZHANG Q,BAI Y,et al.Near-infrared spectroscopy for rapid detection of alcohol extract of Jingutongxiao pills[J].J Beijing Univ Tradit Chin Med,2014,37(11):786
[15] 张强,白雁,雷敬卫,等.筋骨痛消丸水浸出物含量的近红外光谱快速测定[J].中国实验方剂学杂志,2015,21(4):52 ZHANG Q,BAI Y,LEI JW,et al.Rapid determination of water-extract in Jingutongxiao pills by near-infrared spectroscopy[J].Chin J Exp Tradit Med Form,2015,21(4):52
[16] XUE JT,JING Y,LIU YF,et al.Rapid determination of puerarin by near-infrared spectroscopy during percolation and concentration process of Purerariae Lobatae Radix[J].Pharmacogn Mag,2016,12(47):188
[17] 赖秀娣,贾灿潮,林晓菁,等.利用NIRS技术快速测定制何首乌中游离蒽醌含量[J].药物分析杂志,2016,36(12):2215 LAI XD,JIA CC,LIN XJ,et al.Rapid content determination of free anthraquinones in Polygoni Multiflori Radix Praeparata by using NIRS[J].Chin J Pharm Anal,2016,36(12):2215
[18] 贾灿潮,卢慧娟,赵红宁,等.NIRS快速测定制何首乌中二苯乙烯苷的含量[J].计算机与应用化学,2015,32(7):863 JIA CC,LU HJ,ZHAO HN,et al.Rapid determination of the content of 2,3,5,4'-tetrahydroxyl diphenylethylone-2-o-glucoside in Polygoni Multiflori Radix Praeparata by NIRS[J].Comput Appl Chem,2015,32(7):863
[19] 耿姝,陈勇,金叶,等.基于近红外技术的金银花药材多指标成分快速检测[J].中国现代应用药学,2016,33(2):144 GENG S,CHEN Y,JIN YE,et al.Rapid quantitative determination of multi-indicators in Lonicerae Japonicae Flos by near-infrared spectroscopy[J].Chin J Mod Appl Pharm,2016,33(2):144
[20] 朱斌,杨阳,马淑艳,等.近红外漫反射光谱法定量测定金丝桃药材中的金丝桃苷与贯叶金丝桃素[J].药物分析杂志,2013,33(5):889 ZHU B,YANG Y,MA SY,et al.Quantitative determination of hyperoside and hyperforin in Hypericum species by near-infrared diffuse reflectance spectroscopy[J].Chin J Pharm Anal,2013,33(5):889
[21] 张艳,吴永江,吴春艳,等.近红外在线检测丹红注射液醇沉过程中多指标成分的含量变化[J].中国现代应用药学,2015,32(1):67 ZHANG Y, WU YJ, WU CY,et al,Online monitoring multi-component content of Danhong injection in the alcohol precipitation process using near-infrared spectroscopy[J].Chin J Mod Appl Pharm,2015,32(1):67
[22] 姬生国,蔡佳良,周文婷,等.近红外光谱测定藿胆丸中水分含量[J].医药导报,2014,35(5):660 JI SG,CAI JL,ZHOU WT,et al.Content determination of moisture in Huodan pills by near-infrared spectroscopy[J].Her Med,2014,35(5):660
[23] 蔡佳良,李蕾蕾,姬生国.近红外光谱法快速测定广藿香中水分含量[J].医药导报,2012,31(11):1468 CAI JL,LI LL,JI SG.Rapid determination of moisture content in Pogostemon cablin by near-infrared spectroscopy[J].Her Med,2012,31(11):1468
[24] 龚雪,贾灿潮,赖秀娣,等.近红外光谱技术快速测定首乌丸水分含量[J].广东药科大学学报,2017,33(1):61 GONG X,JIA CC,LAI XD,et al.Determination of moisture in Shouwu pills by near-infrared spectroscopy[J].J Guangdong Pharm Univ,2017,33(1):61
[25] 贾灿潮,卢慧娟,林丹,等.近红外光谱技术快速测定何首乌中水分的含量[J].医药导报,2015,34(12):1633 JIA CC,LU HJ,LIN D,et al.Rapid determination of moisture content in Polygoni multiflori Radix by near-infrared spectroscopy[J].Her Med,2015,34(12):1633
[26] 贾灿潮,卢慧娟,姬生国.NIRS快速测定制何首乌中的水分[J].中国实验方剂学杂志,2015,21(16):52 JIA CC,LU HJ,JI SG.Rapid determination of moisture content in Polygoni Multiflori Radix Praeparata by near infrared spectroscopy[J].Chin J Exp Tradit Med Form,2015,21(16):52
[27] 丁银花,毕宇安,曹燕飞,等.AOTF近红外光谱技术快速测定茯苓中的水分[J].药学与临床研究,2014,22(3):209 DING YH,BI YA,CAO YF,et al,Studies on rapid quantitative analysis of the water in Poria cocos by AOTF near-infrared spectroscopy[J].Pharm Clin Res,2014,22(3):209
[28] 杨婵,徐冰,张志强,等.基于移动窗F检验法的中药配方颗粒混合均匀度近红外分析研究[J].中国中药杂志,2016,41(19):3557 YANG C,XU B,ZHANG ZQ,et al,Near-infrared analysis of blending homogeneity of Chinese medicine formula particles based on moving window F test method[J].China J Chin Mater Med,2016,41(19):3557
[29] 马群.安宫牛黄丸生产过程质量评价方法研究[D].北京:北京中医药大学,2007 MA Q.Study on the Methods of Process Quality Evaluation of Angong Niuhuang Wan[D].Beijing:Beijing University of Traditional Chinese Medicine,2007
[30] 马群,乔延江,郝贵奇,等.[J].北京中医药大学学报,2006,29(12):854 MA Q,QIAO YJ,HAO GQ,et al.Application of NIRS in uniformity control of raw powder preparation of Chinese herbal drugs[J].J Beijing Univ Tradit Chin Med,2006,29(12):854
[31] 李云霞,郭艳玲,刘玺.近红外光谱技术监测腰痛宁胶囊生产过程中混合均匀度的研究[J].现代药物与临床,2012,27(4):374 LI YX,GUO YL,LIU X.Monitoring of powder mixture uniformity of Yaotongning capsules in manufacturing process by near-infrared spectroscopy[J].Drugs Clin,2012,27(4):374
[32] 孙玉平,张铁军,曹煌,等.中药辛味药性表达在临证配伍中的应用[J].中草药,2015,46(6):785 SUN YP,ZHANG TJ,CAO H,et al.Expression of pungent-taste herbs and their applications in clinical compatibility[J].Chin Tradit Herb Drug,2015,46(6):785
[33] 盛良,陈建伟,王光耀,等.电子鼻舌检测量化解表药四气五味的探讨[J].南京中医药大学学报,2015,31(5):437 SHENG L,CHEN JW,WANG GY,et al.Study on detection and quantification of four properties and five tastes of drugs for relieving exterior disorder by electronic nose and electronic tongue[J].J Nanjing Univ Tradit Chin Med,2015,31(5):437
[34] 曹煌.基于仿生技术的药味拆分界定表征的初步研究[D].天津:天津医科大学,2016 CAO H.Initial Study on Separation and Characterization of Chinese Herbal Taste Based on Bionics[D].Tianjing:Tianjin Medical University,2016
[35] 伍世元,骆德汉,邓炳荣,等.不同产地和采收期的中药材电子鼻鉴别研究[J].传感技术学报,2011,24(1):10 WU SH,LUO DH,DENG BR,et al.Discrimination of Chinese herbal medicines from different growing areas and harvesting dates based on E-nose[J].Chin J Sens Actuat,2011,24(1):10
[36] 庄家俊,骆德汉,邹宇华.百草油鉴别分类的电子鼻实现方法研究[J].传感器与微系统,2010,29(7):62 ZHUANG JJ,LUO DH,ZOU YH.Classification of luofushan hundred-grass-oil based on E-nose[J].Transd Microsys Technol,2010,29(7):62
[37] LI S,LI SR,WANG GL,et al.Rapid discrimination of Chinese red ginseng and Korean ginseng using an electronic nose coupled with chemometrics[J].J Pharm Biomed Anal,2012,70:605
[38] 范丹君,骆德汉,于昊.一种基于电子鼻的辛味中药材的分类鉴别方法研究[J].广东工业大学学报,2015,32(3):91 FAN DJ,LUO DH,YU H.Classification of pungent Chinese herbals by using electronic nose[J].J Guangdong Univ Technol,2015,32(3):91
[39] 邹慧琴.基于"气"仿生嗅觉系统在中药品质整体评价中的方法学研究[D].北京:北京中医药大学,2013 ZOU HQ.Study on the Methodology of "Qi" Bionic Olfactory System in the Overall Evaluation of TCM Quality[D].Beijing:Beijing University of Traditional Chinese Medicine,2013
[40] LI C,XU F,CAO C,et al.Comparative analysis of two species of Asari Radix et Rhizoma by electronic nose,headspace GC-MS and chemometrics[J].J Pharm Biomed Anal,2013,85(11):231
[41] 刘红秀,姬生国,庄家俊,等.基于仿生嗅觉的中药材鉴别的实现[J].广东药学院学报,2009,25(4):356 LIU HX,JI SG,ZHUANG JJ,et al.To differentiate varieties of Chinese herbal medicine based on bionic olfaction[J].J Guangdong Pharm Univ,2009,25(4):356
[42] CHEN SG,MAO J,HAN BX,et al.Scent analysis of Rosa laevigata through metal oxide sensor array electronic nose[J].Rev Bras Farmacogn,2011,21(6):1150
[43] 杨杰,梁林,李树英,等.基于仿生味觉系统的药物处方开发[J].中国新药杂志,2017,26(7):768 YANG J,LIANG L,LI SY,et al.Application of taste sensing systems in development of pharmaceutical formulation[J].Chin J New Drugs,2017,26(7):768
[44] LIN ZZ,ZHANG Q,LIU RX,et al.Evaluation of the bitterness of traditional Chinese medicines using an E-tongue coupled with a robust partial least squares[J].Regr Sens,2016,16(2):1
[45] 刘瑞新,李慧玲,李学林,等.基于电子舌的穿心莲水煎液的掩味效果评价研究[J].中草药,2013,44(16):2240 LIU RX,LI HL,LI XL,et al.Evaluation on taste-masking effect of Andrographis Herba by electronic tongue[J].Chin Tradit Herb Drug,2013,44(16):2240
[46] 杜瑞超,王优杰,吴飞,等.电子舌对中药滋味的区分辨识[J].中国中药杂志,2013,38(2):154 DU RC,WANG YJ,WU F,et al.Discrimination of traditional Chinese medicinal materials with different tastes based on electronic tongue[J].China J Chin Mater Med,2013,38(2):154
[47] IRINA Y,DMITRY K,LYUDMILA K,et al.Exploring bitterness of traditional Chinese medicine samples by potentiometric electronic tongue and by capillary electrophoresis and liquid chromatography coupled with UV detection[J].Talanta,2016,152,105
[48] 梁晓光,吴飞,王优杰,等.基于现代电子舌技术的传统苦味中药黄连的苦味物质基础研究[J].中国中药杂志,2014,39(17):3326 LIANG XG,WU F,WANG YJ,et al.Research on bitter components from Coptis chinensis based on electronic tongue[J].Chin Tradit Herb Drugs,2014,39(17):3326
[49] 陈朋.近红外分析技术在银蓝调脂胶囊制备过程中的应用研究[D].广州:广州中医药大学,2015 CHEN P.Application of Near-Infrared Spectroscopy Techology in the Production Process of Yin Lan Tiao Zhi capsules[D].Guangzhou:Guangzhou University of Traditional Chinese Medicine,2015
[50] 曹煌,张铁军,张静雅,等.基于电子鼻和电子舌技术的辛味中药气-味的表征研究[J].中草药,2016,47(11):1962 CAO H,ZHANG TJ,ZHANG JY,et al.Characterization of smell and taste of pungent-taste herbs based on electronic nose and electronic tongue[J].Chin Tradit Herb Drug,2016,47(11):1962
[51] 范丹君,骆德汉,于昊.一种基于电子鼻的辛味中药材的分类鉴别方法研究[J].广东工业大学学报,2015,32(3):91 FAN DJ,LUO DH,YU H.Classification of pungent Chinese herbals by using electronic nose[J].J Guangdong Univ Technol,2015,32(3):91
[52] 陈惠勤,骆德汉.基于扩散映射和LDA的辛味中药材鉴别研究[J].计算机技术与发展,2015,25(5):192 CHEN HQ,LUO DH.Research on classification of pungent Chinese herbal medicines based on diffusion maps and LDA[J].Comput Technol Dev,2015,25(5):192
[53] 武琳.基于机器嗅觉/味觉中药材气-味信息融合与品鉴方法的研究[D].广州:广东工业大学,2012 WU L.Classification and Identification of Chinese Herbal medicine by Data Fusion Based on Machine Olfactory and Gustatory[D].Guangzhou:Guangdong University of Technology,2012
[54] 付智慧,李淑军,胡慧华,等.基于电子舌技术的豨莶草炮制前后滋味比较[J].中草药,2017,48(4):673 FU ZH,LI SJ,HU HH,et al.Taste comparison of unprocessed and processed Siegesbeckiae puescens based on electronic tongue[J].Chin Tradit Herb Drug,2017,48(4):673
[55] 李学林,桂新景,刘瑞新,等.基于电子舌法对中药苦味化合物苦度的预测[J].中国新药杂志,2016,25(11):1307 LI XL,GUI XJ,LIU RX,et al.Bitterness intensity prediction of bitter compounds of traditional Chinese medicine based on an electronic tongue[J].Chin J New Drugs,2016,25(11):1307
[56] 李学林,李慧玲,刘瑞新,等.电子舌用于药物掩味效果评价的研究[J].世界科学技术-中医药现代化,2013,15(7):1532 LI XL,LI HL,LIU RX,et al.Study on application of electronic tongue in the evaluation of taste-masking effect of pharmaceutical formulation[J].World Sci Technol Mod Tradit Chin Med Mater Med,2013,15(7):1532
[57] 刘瑞新,李慧玲,李学林,等.基于电子舌的穿心莲水煎液的掩味效果评价研究[J].中草药,2013,44(16):2240 LIU RX,LI HL,LI XL,et al.Evaluation on taste-masking effect of Andrographis Herba by electronic tongue[J].Chin Tradit Herb Drug,2013,44(16):2240
[58] 杜瑞超,王优杰,吴飞,等.电子舌对中药滋味的区分辨识[J].中国中药杂志,2013,38(2):154 DU RC,WANG YJ,WU F,et al.Discrimination of traditional Chinese medicinal materials with different tastes based on electronic tongue[J].Chin Tradit Herb Drug,2013,38(2):154
[59] 李小芳,何倩灵,杨红,等.电子舌在评价大黄颗粒矫味效果中的应用[J].成都中医药大学学报,2011,34(2):80 LI XF,HE QL,YANG H,et al.Application of electronic tongue to evaluating taste-modifying effect of Radix et Rhizoma Rhei granules[J].J Chengdu Univ Tradit Chin Med,2011,34(2):80
[60] USP 32-NF 27[S].2008:622
[61] USP 35-NF 30[S].2012:714
[62] 周帼雄.美、英、欧三部药典近红外光谱分析方法概述[J].中国药品标准,2003,4(2):6 ZHOU GX.Summarization of analytical method of near-infrared in USP,BP and EP[J].Drug Stand China,2003,4(2):6
[63] EP 5.0[S].2005:59
[64] 杨杰,梁林,李树英,等.基于仿生味觉系统的药物处方开发[J].中国新药杂志,2017,26(7):768 YANG J,LIANG L,LI SY,et al.Application of taste sensing systems in development of pharmaceutical formulation[J].Chin J New Drugs,2017,26(7):768
[65] LI KY,WANG WY,LIU YP,et al.Near-infrared spectroscopy as a process analytical technology tool for monitoring the parching process of traditional Chinese medicine based on two kinds of chemical indicators[J].Pharmacogn Mag,2017,50(13):332

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